Charles E. Kaufman Foundation

2024 New Investigator Grant

Grayson Sipe, Ph.D.

Astrocyte-neuron dynamics underlying functional sensory shifts during locomotion


Abstract

This research aims to understand the role of astrocytes, non-neuronal brain cells, in sensory processing and attention shifts during movement. This project will study mice in a virtual reality setting to see how astrocytes and neurons interact during approach behaviors (seeking rewards) and avoidance behaviors (avoiding punishments). The Scientific Advisory Board believes that this research both addresses a largely ignored question in neuroscience and could significantly enhance our understanding of brain function during goal-directed actions.

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